To setup “Automatic replies” in Microsoft Office 365, follow these steps –

1. Log into Office 365 with your email-id and password.
2. Go to settings and select “Automatic replies” as shown in the image.
3. By default, this feature is disabled. To enable this feature select “Send automatic replies“.Specify the starting date/time and ending date/time for this feature to be active. After the end date/time, this feature is automatically disabled.